As the only means of crossing the river Vltava until 1841, Charles Bridge was the most important connection between Prague Castle and the city's Old Town and adjacent areas. This land connection made Prague important as a trade route between Eastern and Western Europe.

The bridge is 516 metres (1,693 ft) long and nearly 10 metres (33 ft) wide. Following the example of the Stone Bridge in Regensburg, it was built as a bow bridge with 16 arches shielded by ice guards. It is protected by three bridge towers, two on the Lesser Quarter side (including the Malá Strana Bridge Tower) and one on the Old Town side, the Old Town Bridge Tower. The bridge is decorated by a continuous alley of 30 statues and statuaries, most of them baroque-style, originally erected around 1700, but now all have been replaced by replicas.

According to the Guinness Book of Records, Prague Castle is the largest ancient castle in the world, occupying an area of almost 70,000 square meters (750,000 square feet), at about 570 meters (1,870 feet) in length and an average of about 130 metres (430 feet) wide. The castle is among the most visited tourist attractions in Prague, attracting over 1.8 million visitors annually.

Old Town Square may be one of the most touristy spots in town, but it’s totally worth the visit for a quick walk through and it’s a must on the list of the best places to visit in Prague. This 12th-century square is home to Old Town Hall, the Church of Our Lady before Týn, the Baroque Church of St Nicholas, the Rococo Kinský Palace, the Gothic House at the Stone Bell and the monument to Jan Hus. 

Petřín Lookout Tower, one of the most prominent landmarks of Prague, was built as part of the Jubilee Exhibition in 1891 as a loose copy inspired by the Eiffel Tower (at a ratio of 1:5). It is 58.70 meters high, and 299 steps lead to its peak, which is at the same altitude as the real Eiffel Tower. The view from its top overlooks not only the whole city, but on a clear day you can see nearly all of Bohemia.

Historic fort in Prague, Czech Republic, just over 3 km southeast of Prague Castle, on the east bank of the Vltava River. It was probably built in the 10th century. Inside the fort is the Basilica of St. Peter and St. Paul and the Vyšehrad Cemetery, containing the remains of many famous Czechs, such as Antonín Dvořák, Bedřich Smetana, Karel Čapek, and Alphonse Mucha. It also contains Prague's oldest Rotunda of St. Martin, from the 11th century.

Letná Park (Czech: Letenské sady) is a large park on Letná hill, built on a plateau above steep embankments along the Vltava River in Prague, Czech Republic.

"Leten", originally called "summer camp" or "place to sunbathe" gained its importance in the Middle Ages, when the first military camps were located there due to their strategic location.  The areas were mainly vineyards and gardens. It was not until the end of the 19th century that it began to be systematically colonized. Over time, the plains of this area of the city became a place of meeting, entertainment and recreation.

The Lennon Wall (Czech: Lennonova zeď) or John Lennon Wall (Czech: Zeď Johna Lennona), located at Velkopřevorské náměstí (Grand Priory Square), Malá Strana, is a historic legal graffiti wall in Prague, Czechia. After the 1980 murder of John Lennon a mural of Lennon was painted by an unknown artist onto the wall and as more people expanded upon it, the wall slowly became a place for free expression of then communist Czechoslovakia. It has historically been used for demonstrations and carries a central theme of John Lennon, but it also features designs relating to local and global causes such as global warming. The wall has also inspired other walls across the globe, such as the Hong Kong Lennon wall.

The wall is owned by the Sovereign Military Order of Malta, which until 2019 allowed all graffiti. As of the latest reconstruction, the wall exists as a semi-legal graffiti wall; spray painting has been banned and only some areas of the wall are allowed to be used by the public.

Jews are believed to have settled in Prague as early as the 10th century. The first pogrom was in 1096 (the first crusade) and eventually they were concentrated within a walled Ghetto. In 1262, Přemysl Otakar II issued a Statuta Judaeorum which granted the community a degree of self-administration. The ghetto was most prosperous towards the end of the 16th century when the Jewish Mayor, Mordecai Maisel, became the Minister of Finance and a very wealthy man. His money helped develop the ghetto.